Cover [Abstract] Document Information [Table] Document Information [Line Items] Entity Central Index Key Document Type Document Quarterly Report Document Period End Date Document Transition Report Entity File Number Entity Registrant Name Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Address, Address Line One Entity Address, City or Town Entity Address, State or Province Entity Address, Postal Zip Code City Area Code Local Phone Number Title of 12(b) Security Trading Symbol Security Exchange Name Entity Current Reporting Status Entity Interactive Data Current Entity Filer Category Entity Small Business Entity Emerging Growth Company Entity Shell Company Entity Listing, Par Value Per Share Entity Common Stock, Shares Outstanding Current Fiscal Year End Date Document Fiscal Year Focus Document Fiscal Period Focus Amendment Flag Statement of Financial Position [Abstract] Statement [Table] Statement [Line Items] Assets [Abstract] Assets, Current [Abstract] Current assets: Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Cash and cash equivalents Available-for-sale Securities, Debt Securities, Current Marketable securities Accounts Receivable, Net, Current Accounts receivable, net Unbilled Receivables, Including Reimbursable Costs, Current Unbilled Receivables, Including Reimbursable Costs, Current Unbilled accounts receivable Inventory, Net Inventory Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Assets, Current Total current assets Available-for-sale Securities, Debt Securities, Noncurrent Marketable securities Property, Plant and Equipment, Net Property and equipment, net Operating lease right-of-use assets, net Operating lease right-of-use assets, net Restricted Cash, Noncurrent Restricted cash Other Assets, Noncurrent Other assets Total assets Total assets Liabilities and Equity [Abstract] Liabilities, Current [Abstract] Current liabilities: Accounts Payable, Current Accounts payable Accrued Liabilities, Current Accrued expenses Total Current portion of operating lease liabilities Current portion of operating lease liabilities Contract with Customer, Liability, Current Deferred revenue, current Total current liabilities Total current liabilities Operating lease liabilities, net of current portion Operating lease liabilities, net of current portion Contract with Customer, Liability, Noncurrent Deferred revenue, net of current portion Other Liabilities, Noncurrent Other long-term liabilities Total liabilities Total liabilities Commitments and Contingencies Commitments (Note 15) Stockholders' Equity Attributable to Parent [Abstract] Stockholders' equity: Preferred Stock, Value, Outstanding Preferred stock, $0.001 par value; 5,000,000 shares authorized; no shares issued and outstanding Common Stock, Value, Issued Common stock, $0.001 par value; 120,000,000 shares authorized; 58,814,766 and 57,793,533 shares issued and outstanding at September 30, 2021 and December 31, 2020, respectively Additional Paid in Capital Additional paid-in capital Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive loss Retained Earnings (Accumulated Deficit) Accumulated deficit Stockholders' Equity Attributable to Parent Ending Balance Beginning Balance Total stockholders' equity Liabilities and Equity Total liabilities and stockholders' equity Preferred Stock, Number of Shares, Par Value and Other Disclosures [Abstract] Preferred Stock Disclosures Preferred Stock, Par or Stated Value Per Share Preferred stock, par value (in dollars per share) Preferred Stock, Shares Authorized Preferred stock, shares authorized (in shares) Preferred Stock, Shares Issued Preferred stock, shares issued (in shares) Preferred Stock, Shares Outstanding Preferred stock, shares outstanding (in shares) Common Stock, Number of Shares, Par Value and Other Disclosures [Abstract] Common Stock Disclosures Common Stock, Par or Stated Value Per Share Common stock, par value (in dollars per share) Common Stock, Shares Authorized Common stock, shares authorized (in shares) Common Stock, Shares, Issued Ending Balance (in shares) Beginning Balance (in shares) Common stock, shares issued (in shares) Common Stock, Shares, Outstanding Common Stock, shares outstanding (in shares) Income Statement [Abstract] Product and Service [Axis] Product and Service [Domain] Product revenue, net Collaboration [Member] Collaboration revenue Revenues [Abstract] Revenues Revenues: Revenue from Contract with Customer, Including Assessed Tax Revenue Operating Expenses [Abstract] Cost and operating expenses: Cost of Goods and Services Sold Cost of sales Research and Development Expense Research and development Selling, General and Administrative Expense Selling, general and administrative Collaboration Profit (Loss) Sharing Collaboration Profit (Loss) Sharing Collaboration loss sharing Costs and Expenses Total cost and operating expenses Nonoperating Income (Expense) [Abstract] Other income (expense): Interest Income (Expense), Net Interest income, net Other Nonoperating Income (Expense) Other expense, net Nonoperating Income (Expense) Total other income Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Income (loss) before income taxes Income Tax Expense (Benefit) Income tax expense Net Income (Loss) Attributable to Parent Net loss Net income (loss) Net income (loss) Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Other comprehensive income (loss): Other Comprehensive Income (Loss), Unrealized Holding Gain (Loss) on Securities Arising During Period, Net of Tax Unrealized gain (losses) on available-for-sale investments Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax Currency translation adjustments Comprehensive Income (Loss), Net of Tax, Attributable to Parent Comprehensive income (loss) Earnings Per Share, Basic Net income (loss) per share - basic (in dollars per share) Earnings Per Share, Diluted Net income (loss) per share - diluted (in dollars per share) Weighted Average Number of Shares Outstanding, Basic Weighted-average number of common shares used in net income (loss) per share - basic (in shares) Weighted average shares outstanding - basic (in shares) Weighted Average Number of Shares Outstanding, Diluted Weighted-average number of common shares used in net income (loss) per share - diluted (in shares) Weighted average shares outstanding - diluted (in shares) Statement of Stockholders' Equity [Abstract] Equity Components [Axis] Equity Component [Domain] Common Stock Additional Paid-In Capital Accumulated Other Comprehensive Loss Accumulated Deficit Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity Stock Issued During Period, Value, Share-based Compensation, Net of Forfeitures Issuance of common stock under stock plan Stock Issued During Period, Shares, Share-based Compensation, Net of Forfeitures Issuance of common stock under stock plan (in shares) Stock Issued During Period, Value, Employee Stock Purchase Plan Purchase of common stock under ESPP Stock Issued During Period, Shares, Employee Stock Purchase Plans Purchase of common stock under ESPP (in shares) Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition Stock-based compensation expense Stock Issued During Period, Value, New Issues Issuance of common stock Stock Issued During Period, Shares, New Issues Stock issued (in shares) Issuance of common stock (in shares) Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Other comprehensive income Adjustments to Additional Paid in Capital, Other Other Statement of Cash Flows [Abstract] Net Cash Provided by (Used in) Operating Activities [Abstract] Cash flows from operating activities Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net income (loss) Adjustments, Noncash Items, to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities: Depreciation, Depletion and Amortization Depreciation and amortization Lease, Right-of-Use Asset, Amortization. Lease, Right-of-Use Asset, Amortization Noncash lease expense Share-based Compensation Stock-based compensation Other Operating Activities, Cash Flow Statement Other Increase (Decrease) in Operating Capital [Abstract] Changes in assets and liabilities: Increase (Decrease) in Accounts Receivable Accounts receivable The increase (decrease) during the reporting period of the amount of customer assets. Increase (Decrease) in Customer Assets Unbilled accounts receivable Increase (Decrease) in Inventories Inventory Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other current assets Increase (Decrease) in Other Noncurrent Assets Other assets Increase (Decrease) in Accounts Payable Accounts payable Increase (Decrease) in Accrued Liabilities Accrued expenses Increase (Decrease) in Contract with Customer, Liability Deferred revenue Increase (Decrease) in Operating Lease Liability Operating lease liabilities Net Cash Provided by (Used in) Operating Activities Net cash provided by (used in) operating activities Net Cash Provided by (Used in) Investing Activities [Abstract] Cash flows from investing activities Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Payments to Acquire Available-for-sale Securities, Debt Purchases of investments Proceeds from Maturities, Prepayments and Calls of Available-for-sale Securities Maturities of investments Proceeds from the maturities of debt securities Net Cash Provided by (Used in) Investing Activities Net cash provided by (used in) investing activities Net Cash Provided by (Used in) Financing Activities [Abstract] Cash flows from financing activities Proceeds from Issuance of Common Stock, Net of Underwriting Discounts, Commissions, and Offering Expenses Proceeds from Issuance of Common Stock, Net of Underwriting Discounts, Commissions, and Offering Expenses Proceeds from public offerings of common stock, net of issuance cost Net Proceeds from Stock Option Exercises and Employee Stock Purchase Plan Net Proceeds from Stock Option Exercises and Employee Stock Purchase Plan Net proceeds from stock option exercises and employee stock purchase plan Proceeds from Issuance of Private Placement Issuance of common stock related to collaboration agreement Payments of Stock Issuance Costs Payment of offering costs Net Cash Provided by (Used in) Financing Activities Net cash provided by financing activities Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Net increase (decrease) in cash, cash equivalents, and restricted cash Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents Cash, cash equivalents and restricted cash at end of period Cash, cash equivalents and restricted cash at beginning of period Total cash, cash equivalents, and restricted cash shown in condensed consolidated statements of cash flows Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents Effect of exchange rate changes on cash, cash equivalents and restricted cash Supplemental Cash Flow Information [Abstract] Supplemental cash flow information Capital Expenditures Incurred but Not yet Paid Property and equipment purchases unpaid at period end Income Taxes Paid, Net Cash paid for taxes, net Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Abstract] Reconciliation of cash, cash equivalents, and restricted cash Organization, Consolidation and Presentation of Financial Statements [Abstract] Disclosure Text Block [Abstract] Disclosure Text Block Nature of Operations [Text Block] Nature of Business Accounting Policies [Abstract] Organization, Consolidation, Basis of Presentation, Business Description and Accounting Policies [Text Block] Summary of Significant Accounting Policies and Recent Accounting Pronouncements Investments, Debt and Equity Securities [Abstract] Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] Marketable Securities Fair Value Disclosures [Abstract] Fair Value Disclosures [Text Block] Fair Value of Financial Instruments Revenue from Contract with Customer [Abstract] Allowance for Credit Losses [Text Block] Product Revenue Reserves and Allowances Inventory Disclosure [Abstract] Inventory Disclosure [Text Block] Inventory Restricted Cash and Cash Equivalents [Abstract] Restricted Assets Disclosure [Text Block] Restricted Cash Payables and Accruals [Abstract] Accounts Payable and Accrued Liabilities Disclosure [Text Block] Accrued Expenses Collaborative Arrangement Disclosure [Abstract] Collaborative Arrangement Disclosure [Abstract] Collaborative Arrangement Disclosure [Text Block] Collaboration and License Agreements Disclosure of Compensation Related Costs, Share-based Payments [Abstract] Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Stock-based Compensation Earnings Per Share [Abstract] Earnings Per Share [Text Block] Net Income (Loss) Per Share Income Tax Disclosure [Abstract] Income Tax Disclosure [Text Block] Income Taxes Leases [Abstract] Lessee, Operating Leases [Text Block] Leases Commitments and Contingencies Disclosure [Abstract] Commitments Disclosure [Text Block] Commitments Policy Text Block [Abstract] Policy Text Blocks Basis of Accounting, Policy [Policy Text Block] Basis of Presentation Use of Estimates, Policy [Policy Text Block] Use of Estimates Disclosure of significant accounting policies. Significant Accounting Policy [Policy Text Block] Significant Accounting Policies Disclosure of accounting policy for reclassification. Reclassifications Policy Policy [Text Block] Reclassification New Accounting Pronouncements, Policy [Policy Text Block] New Accounting Pronouncements Table Text Block [Abstract] Table Text Blocks Debt Securities, Available-for-sale [Table Text Block] Schedule of marketable securities Fair Value Measurements, Recurring and Nonrecurring [Table Text Block] Schedule of financial instruments measured at fair value Disaggregation of Revenue [Table] Disaggregation of Revenue [Line Items] Disaggregation of Revenue [Table Text Block] Summary of revenue recognized Contract with Customer, Asset and Liability [Table Text Block] Summary of contract assets and/or contract liabilities Schedule of product revenue allowance and reserve categories Tabular disclosure of current and noncurrent inventory. Schedule of Inventory, Current and Noncurrent [Table Text Block] Schedule of capitalized inventory Schedule of Accrued Liabilities [Table Text Block] Schedule of accrued expenses Schedule of Collaborative Arrangements and Non-collaborative Arrangement Transactions [Table] Counterparty Name [Axis] Counterparty Name [Domain] Roche [Member] Roche Roche, Collaboration (Pralsetnib) Agreement [Member] Roche, Collaboration (Pralsetnib) Agreement Roche, Collaboration and License (Immunotherapy) Agreement [Member] Roche, Collaboration and License (Immunotherapy) Agreement C Stone [Member] C Stone Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] Collaboration Agreements Tabular disclosure of manufacturing services related to the global development activities. Schedule of Manufacturing Services Related to Agreement Activities [Table Text Block] Summary of manufacturing and research and development services related to the global development activities Tabular disclosure of collaboration loss sharing. Schedule of Collaboration Loss Sharing [Table Text Block] Schedule of collaboration loss sharing Tabular disclosure of amounts recognized as reductions to expenses in collaborative arrangements. Schedule of Amounts Recognized as Reductions to Expenses, Collaborative Arrangement [Table Text Block] Schedule of amounts recognized as reductions to expenses Share-based Compensation, Stock Options, Activity [Table Text Block] Summary of stock option activity Schedule of Nonvested Restricted Stock Units Activity [Table Text Block] Summary of restricted stock units activity Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block] Summary of stock-based compensation expense, allocation by type of awards and recognition in statements of operations Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Schedule of net income (loss) and the number of shares used to compute basic and diluted net income (loss) per share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Schedule of common stock equivalents excluded from calculation of diluted net loss per share applicable to common stockholders Lease, Cost [Table Text Block] Summary of lease expenses and cash flow and weighted average information Investments and Cash [Abstract] Cash, cash equivalents and marketable securities Investments and Cash Cash, cash equivalents and marketable securities Debt Securities, Available-for-sale [Table] Investment Type [Axis] Investments [Domain] U.S. government agency securities U.S. Treasury obligations Debt Securities, Available-for-sale [Line Items] Debt Securities, Available-for-sale, Fair Value to Amortized Cost [Abstract] Marketable securities, available-for-sale: Debt Securities, Available-for-Sale, Amortized Cost, after Allowance for Credit Loss Amortized cost Available-for-sale Debt Securities, Accumulated Gross Unrealized Gain, before Tax Unrealized gain Available-for-sale Debt Securities, Accumulated Gross Unrealized Loss, before Tax Unrealized losses Available-for-sale Securities, Debt Securities Marketable securities, available-for-sale Fair value Available-for-sale, Securities in Unrealized Loss Positions, Qualitative Disclosure, Number of Positions [Abstract] Unrealized loss position, number of positions Debt Securities, Available-for-sale, Unrealized Loss Position, Number of Positions Number of held securities in an unrealized loss position Debt Securities, Available-for-sale, Continuous Unrealized Loss Position, 12 Months or Longer, Number of Positions Number of held securities in an unrealized loss position for 12 months or longer Available-for-sale Securities, Continuous Unrealized Loss Position, Accumulated Loss [Abstract] Unrealized loss position, aggregate fair value Debt Securities, Available-for-sale, Unrealized Loss Position, Accumulated Loss Unrealized loss position Other-than-temporary Impairment Loss, Debt Securities, Available-for-sale, Reportable Items [Abstract] Other than Temporary Impairment Losses, Investments, Available-for-sale Securities [Abstract] Other-than-temporary impairment loss, debt securities, available-for-sale securities Other-than-temporary Impairment Loss, Debt Securities, Available-for-sale Other-than-temporary impairment loss, debt securities, available-for-sale Debt Securities, Available-for-sale, Maturity, Fair Value, Rolling Maturity [Abstract] Investments, available-for-sale Number of investments in debt securities measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale). Debt Securities, Available-for-sale, Number of Positions Securities with remaining maturities greater than one year Debt Securities, Available-for-sale, Maturity, Allocated and Single Maturity Date, Rolling after One Through Five Years, Fair Value Aggregate fair value with remaining maturities greater than one year Proceeds from Sale and Maturity of Debt Securities, Available-for-sale [Abstract] Proceeds from the maturities of debt securities Debt Securities, Available-for-sale, Realized Gain (Loss) [Abstract] Realized gains (losses) from maturities of debt securities Debt Securities, Available-for-sale, Realized Gain (Loss) Realized gains (losses) from maturities of debt securities Fair Value Measurements, Recurring and Nonrecurring [Table] Measurement Frequency [Axis] Fair Value, Measurement Frequency [Domain] Recurring Fair Value, Hierarchy [Axis] Fair Value Hierarchy [Domain] Fair Value, Inputs, Level 1, 2 and 3 [Member] Active Markets (Level 1) Observable Inputs (Level 2) Cash and Cash Equivalents [Axis] Cash and Cash Equivalents [Domain] Cash Equivalents [Member] Money market funds Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value, Net Asset (Liability) [Abstract] Fair Value of Financial Instruments Cash and Cash Equivalents, Fair Value Disclosure Cash equivalents Assets, Fair Value Disclosure Total AYVAKIT and AYVAKYT [Member] AYVAKIT and AYVAKYT AYVAKIT and AYVAKYT GAVRETO [Member] GAVRETO GAVRETO Contract with Customer, Asset, Allowance for Credit Loss [Roll Forward] Product revenue allowance and reserve Contract with Customer, Asset, Allowance for Credit Loss Ending balance Beginning balance Revenue-related reserves Contract with Customer, Asset, Credit Loss Expense (Reversal) Provision related to sales in the current period Contract with Customer, Asset, Allowance for Credit Loss, Recovery Credits and payments made Balance Sheet Location [Axis] Balance Sheet Location [Domain] Accounts Receivable, Net Accrued Expenses Contract with Customer, Asset, after Allowance for Credit Loss [Abstract] Revenue-related reserves Inventory, Noncurrent [Abstract] Inventory Inventory, Current and Noncurrent, Raw Materials, Net of Reserves Inventory, Current and Noncurrent, Raw Materials, Net of Reserves Raw materials Inventory, Current and Noncurrent, Work in Process, Net of Reserves Inventory, Current and Noncurrent, Work in Process, Net of Reserves Work in process Inventory, Current and Noncurrent, Finished Goods, Net of Reserves Inventory, Current and Noncurrent, Finished Goods, Net of Reserves Finished goods Inventory, Current and Noncurrent, Net Inventory, Current and Noncurrent, Net Total Inventory, Noncurrent Other assets Inventory, Net [Abstract] Inventory Inventory Write-down Inventory write-down Restricted Cash [Abstract] Restricted cash Restricted Cash Restricted cash Accrued Liabilities, Current [Abstract] Accrued Expenses External Research, Development and Commercial Contract Costs, Current External Research, Development and Commercial Contract Costs, Current Research, development and commercial contract costs Employee-related Liabilities, Current Employee compensation Accrued Professional Fees, Current Accrued professional fees Amount of accrued accumulated credit loss for right to consideration in exchange for good or service transferred to customer when right is conditioned on something other than passage of time. Accrued Contract With Customer Asset Accumulated Allowance For Credit Loss Revenue-related reserves Other Accrued Liabilities, Current Other Type of Arrangement and Non-arrangement Transactions [Axis] Arrangements and Non-arrangement Transactions [Domain] Collaborative Arrangement Clementia [Member] Clementia Collaborative Arrangement, Upfront Payment, Cash Payment Received Collaborative Arrangement, Upfront Payment, Cash Payment Received Collaborative arrangement, upfront payment, cash payment received Collaborative Arrangement, Milestones, Cash Payments Received Collaborative Arrangement, Milestones, Cash Payments Received Collaborative arrangement, milestones, cash payments received Collaborative Arrangement, Milestones, Contingent Payments Eligible to Receive Collaborative Arrangement, Milestones, Contingent Payments Eligible to Receive Collaborative arrangement, milestones, contingent payments eligible to receive Collaborative Arrangement, Milestones, Development and Regulatory Milestones, Contingent Payments Eligible to Receive Collaborative Arrangement, Milestones, Development and Regulatory Milestones, Contingent Payments Eligible to Receive Collaborative arrangement, milestones, development and regulatory milestones, contingent payments eligible to receive Collaborative Arrangement, Milestones, Sales-based Milestones, Contingent Payments Eligible to Receive Collaborative Arrangement, Milestones, Sales-based Milestones, Contingent Payments Eligible to Receive Collaborative arrangement, milestones, sales-based milestones, contingent payments eligible to receive Collaborative Arrangement, Option Fees and Milestones, Contingent Payments Eligible to Receive Collaborative Arrangement, Option Fees and Milestones, Contingent Payments Eligible to Receive Collaborative arrangement, option fees and milestones, contingent payments eligible to receive Collaborative Arrangement, Milestones, Achieved Collaborative Arrangement, Milestones, Achieved Collaborative arrangement, milestones, achieved Collaborative Arrangement, Milestones, Specified Regulatory and Commercialization Milestones, Achieved Collaborative Arrangement, Milestones, Specified Regulatory and Commercialization Milestones, Achieved Collaborative arrangement, milestones, specified regulatory and commercialization milestones, achieved Collaborative Arrangement, Milestones, Research Milestones, Achieved Collaborative Arrangement, Milestones, Research Milestones, Achieved Collaborative arrangement, milestones, research milestones, achieved Collaborative Arrangement, Percentage of Global Development Costs Shared, Entity Collaborative Arrangement, Percentage of Global Development Costs Shared, Entity Collaborative arrangement, percentage of global development costs shared, entity (as a percent) Collaborative Arrangement, Percentage of Global Development Costs Shared, Counterparty Collaborative Arrangement, Percentage of Global Development Costs Shared, Counterparty Collaborative arrangement, percentage of global development costs shared, counterparty (as a percent) Collaborative Arrangement, Inventory Purchased by Counterparty Collaborative Arrangement, Inventory Purchased by Counterparty Collaborative arrangement, inventory purchased by counterparty Collaborative Arrangement, Licensed Product Term from First Commercial Sale Collaborative arrangement, licensed product term from first commercial sale Collaborative Arrangement, License Option Rights, Number Collaborative Arrangement, License Option Rights, Number Collaborative arrangement, license option rights, number Collaborative Arrangement, Collaboration Programs with Exclusive Commercialization Rights, Number Collaborative Arrangement, Collaboration Programs with Exclusive Commercialization Rights, Number Collaborative arrangement, collaboration programs with exclusive commercialization rights, number Collaborative Arrangement, Collaboration Programs, Number Collaborative Arrangement, Collaboration Programs, Number Collaborative arrangement, collaboration programs, number Collaborative Arrangement, Collaboration Programs, Licensed Products, Commercialization Rights, Counterparty Exercises Option, Counterparty Receives Worldwide Exclusivity, Number Collaborative Arrangement, Collaboration Programs, Licensed Products, Commercialization Rights, Counterparty Exercises Option, Counterparty Receives Worldwide Exclusivity, Number Collaborative arrangement, collaboration programs, licensed products, commercialization rights, counterparty exercises option, counterparty receives worldwide exclusivity, number Collaborative Arrangement, Termination, Counterparty Written Notice Period Collaborative Arrangement, Termination, Counterparty Written Notice Period Collaborative arrangement, termination, counterparty written notice period Collaborative Arrangement, Termination, Counterparty Written Notice Period, After Option Exercise, If Licensed Products Have Not Been Commercially Sold Collaborative Arrangement, Termination, Counterparty Written Notice Period, After Option Exercise, If Licensed Products Have Not Been Commercially Sold Collaborative arrangement, termination, counterparty written notice period, after option exercise, if licensed products have not been commercially sold Collaborative Arrangement, Termination, Counterparty Written Notice Period, After Option Exercise, If Licensed Products Have Been Commercially Sold Collaborative Arrangement, Termination, Counterparty Written Notice Period, After Option Exercise, If Licensed Products Have Been Commercially Sold Collaborative arrangement, termination, counterparty written notice period, after option exercise, if licensed products have been commercially sold Collaborative Arrangement, Transaction Price Collaborative Arrangement, Transaction Price Collaborative arrangement, transaction price Collaborative Arrangement, Transaction Price, Upfront Payment Collaborative Arrangement, Transaction Price, Upfront Payment Collaborative arrangement, transaction price, upfront payment Collaborative Arrangement, Transaction Price, Stock Issued, Premium on Sale of Stock to Counterparty Collaborative Arrangement, Transaction Price, Stock Issued, Premium on Sale of Stock to Counterparty Collaborative arrangement, transaction price, stock issued, premium on sale of stock to counterparty Collaborative Arrangement, Transaction Price, Milestone Payments Receivable Collaborative Arrangement, Transaction Price, Milestone Payments Receivable Collaborative arrangement, transaction price, milestone payments receivable Collaborative Arrangement, Transaction Price, Inventory Purchased by Counterparty, Existing Manufacturing Inventory Collaborative Arrangement, Transaction Price, Inventory Purchased by Counterparty, Existing Manufacturing Inventory Collaborative arrangement, transaction price, inventory purchased by counterparty, existing manufacturing inventory Collaborative Arrangement, Transaction Price, Inventory Purchased by Counterparty, In-process Manufacturing Inventory Collaborative Arrangement, Transaction Price, Inventory Purchased by Counterparty, In-process Manufacturing Inventory Collaborative arrangement, transaction price, inventory purchased by counterparty, in-process manufacturing inventory Subsidiary or Equity Method Investee, Sale of Stock by Subsidiary or Equity Investee [Table] Sale of Stock [Axis] Sale of Stock [Domain] Private Placement Subsidiary, Sale of Stock [Line Items] Sale of Stock Share Price Share price (in dollars per share) Stock Issued During Period, Value, New Issues, Purchase Consideration Stock Issued During Period, Value, New Issues, Purchase Consideration Purchase consideration Stock Issued During Period, Value, New Issues, Premium Stock Issued During Period, Value, New Issues, Premium Share purchase consideration, premium Collaborative Arrangement, Manufacturing and Research and Development Services Related to Global Development Activities, Net of Cost Sharing Payments Collaborative Arrangement, Manufacturing and Research and Development Services Related to Global Development Activities, Net of Cost Sharing Payments Manufacturing and research and development services related to global development activities, net of expenses payable License [Member] Upfront License [Member] Upfront license revenue License Milestone [Member] License milestone revenue Territory-specific Activities, Manufacturing Services [Member] Territory-specific activities, manufacturing services Territory-specific Activities, Manufacturing and Other Services [Member] Territory-specific activities, manufacturing and other services Territory-specific activities, manufacturing and other services Royalty Collaborative Arrangement, Commercialization, Reduction in Selling, General and Administrative Expenses Collaborative Arrangement, Commercialization, Reduction in Selling, General and Administrative Expenses Collaborative arrangement, commercialization, reduction in selling, general and administrative expenses Collaborative Arrangement, Global Development Activities, Reduction in Research and Development Expenses Collaborative Arrangement, Global Development Activities, Reduction in Research and Development Expenses Collaborative arrangement, global development activities, reduction in research and development expenses Contract with Customer, Contract Asset, Contract Liability, and Receivable [Abstract] Change in Contract with Customer, Asset and Liability [Abstract] Change in Contract with Customer, Liability [Abstract] Change in Contract with Customer, Liability Contract with Customer, Liability, Revenue Recognized Amounts included in the contact liability at the beginning of the period Contract with Customer, Liability [Abstract] Contract Liability Contract with Customer, Liability Deferred revenue Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Table] Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis] Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items] Performance Obligations Collaborative Arrangement, Material Promises, Number Collaborative Arrangement, Material Promises, Number Collaborative arrangement, material promises, number Collaborative Arrangement, Material Promises, Manufacturing Activities, Term Collaborative Arrangement, Material Promises, Manufacturing Activities, Term Collaborative arrangement, material promises, manufacturing activities, term Collaborative Arrangement, Material Components, Number Collaborative Arrangement, Material Components, Number Collaborative arrangement, material components, number Revenue, Performance Obligation, Performance Obligations, Number Revenue, Performance Obligation, Performance Obligations, Number Revenue, performance obligation, performance obligations, number Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Period Revenue, remaining performance obligation, expected timing of satisfaction, period Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Plan Name [Axis] Plan Name [Domain] Represents the stock option and incentive plan approved in 2015. 2015 Stock Option and Incentive Plan Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award, Additional General Disclosures [Abstract] Stock-based compensation Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized Initial shares of common stock authorized for issuance of stock awards (in shares) The percentage of additional shares authorized for issuance under an established share-based compensation plan. Share-based Compensation Arrangement by Share-based Payment Award, Percentage of Additional Shares Authorized Increase in number of shares available for grant (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized Increase in number of shares available for grant (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant Number of shares available for grant (in shares) Inducement Plan, 2020 [Member] 2020 Inducement Plan Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward] Shares Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Outstanding at end of period (in shares) Outstanding at beginning of period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Granted (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Exercised (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Other Increases (Decreases) in Period Cancelled (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Weighted-Average Exercise Price Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Outstanding at end of period (in dollars per share) Outstanding at beginning of period (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Granted (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Exercised (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Other Share Increase (Decrease) in Period, Weighted Average Exercise Price Cancelled (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract] Additional disclosures Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number Shares - Exercisable (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price Weighted-Average Exercise Price - Exercisable (in dollars per share) Award Type [Axis] Equity Award [Domain] Restricted Stock Units Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized [Abstract] Stock-based compensation Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized Total unrecognized compensation cost related to non-vested stock awards Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options Total unrecognized compensation cost related to non-vested stock option awards Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition Weighted-average period over which unrecognized compensation cost will be recognized Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Shares Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number Unvested at end of period (in shares) Unvested at beginning of period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period Granted (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period Vested (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeited in Period Forfeited (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Weighted-Average Grant Date Fair Value Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Unvested at end of period (in dollars per share) Unvested at beginning or period (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Granted (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Vested (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Forfeited (in dollars per share) Employee Stock Common Stock, Capital Shares Reserved for Future Issuance Number of common shares reserved for future issuance (in shares) Represents the annual cumulative increase for common stock issuance, as a percentage of the number of shares of common stock issued and outstanding. Annual Cumulative Increase Percentage of Number of Share of Common Stock Issued and Outstanding Annual increase for common stock for issuance (as a percent) Increase in aggregate number of common shares reserved for future issuance. Common Stock Increase Capital Shares Reserved for Future Issuance Increase of common shares reserved for future issuance (in shares) Employee Service Share-based Compensation, Aggregate Disclosures [Abstract] Total stock based compensation expense Allocated Share-based Compensation Expense Stock-based compensation expense included in total cost and operating expenses Stock-based compensation expense Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Stock Options Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] Share-based Payment Arrangement, Expensed and Capitalized, Amount Subtotal Share-based Payment Arrangement, Amount Capitalized Capitalized stock-based compensation costs Income Statement Location [Axis] Income Statement Location [Domain] Research and Development Selling, General and Administrative General and Administrative Expense Net Income (Loss) Available to Common Stockholders, Diluted [Abstract] Net income (loss) - basic and diluted Net Income (Loss) Available to Common Stockholders, Basic Net income (loss) - basic Net Income (Loss) Available to Common Stockholders, Diluted Net income (loss) - diluted Weighted Average Number of Shares Outstanding, Diluted [Abstract] Weighted average shares outstanding Incremental Weighted Average Shares Attributable to Dilutive Effect [Abstract] Effect of dilutive securities: Incremental Common Shares Attributable to Dilutive Effect of Share-based Payment Arrangements Effect of dilutive securities (in shares) Earnings Per Share, Basic [Abstract] Net income (loss) per share - basic Earnings Per Share, Diluted [Abstract] Net income (loss) per share - diluted Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Antidilutive Securities [Axis] Antidilutive Securities, Name [Domain] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Earnings Per Share, Basic and Diluted, Other Disclosures [Abstract] Antidilutive securities excluded from computation of earnings per share Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Antidilutive securities excluded from computation of earnings per share Lessee, Lease, Description [Table] Range [Axis] Range [Domain] Minimum Maximum Lessee, Lease, Description [Line Items] Lessee, Operating Lease, Description [Abstract] Leases Lessee, Operating Lease, Remaining Lease Term Operating lease remaining lease term Operating leases cost: Operating Lease, Cost Lease cost Sublease Income Sublease income Lease, Cost Net lease cost Cash Flow, Operating Activities, Lessee [Abstract] Leases Operating lease liabilities Cash paid for amounts included in the measurement of lease liabilities, operating cash flows from operating leases Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Lease liabilities arising from obtaining right-of-use assets, operating leases Lessee Disclosure [Abstract] Leases Operating Lease, Weighted Average Remaining Lease Term Weighted average remaining lease term in years Operating Lease, Weighted Average Discount Rate, Percent Weighted average discount rate